Sex-Related Differences in Myocardial Remodeling

sex differences in acute myocardial infarction

Sex‐related differences in intrinsic myocardial properties influence cardiac function in middle‐aged rats during infarction‐induced left ventricular remodeling

We previously determined that residual left ventricular (LV) myocardium of middle-aged rats had sex-related differences in regional tissue properties 4 weeks after a large myocardial infarction (MI). However, the impact of such differences on cardiac performance remained unclear. Therefore, our current study aimed to elucidate whether sex-related changes in MI-induced myocardial remodeling can ...

Sex differences in Acute Myocardial Infarction

Coronary Artery Disease (CAD) is the common cause of mortality and disability worldwide. Usually women with CAD are older and have more risk factors than men. If they have diabetes, hypertriglyceridemia and metabolic syndrome, they would be at greater risk of CAD than men (1). Experimental studies have shown that gender has an important role in cardiovascular physiology and pathology. On the ot...

Sex differences in endothelial STAT3 mediate sex differences in myocardial inflammation.

Recent studies have shown that females have improved myocardial functional recovery, TNF receptor 1 (TNFR1) signaling resistance, and increased STAT3 phosphorylation following acute ischemia/reperfusion (I/R) compared with males. We hypothesized that 1) STAT3 deficiency in endothelial cells (EC) impairs myocardial functional recovery in both sexes, 2) EC STAT3 deficiency equalizes sex differenc...

Sex-related differences in chromatic sensitivity.

Generally women are believed to be more discriminating than men in the use of color names and this is often taken to imply superior color vision. However, if both X-chromosome linked color deficient males (8%) and females (<1%) as well as heterozygote female carriers (15%) are excluded from comparisons, then differences between men and women in red-green (RG) color discrimination have been repo...